Cures Start Here.
At Fred Hutchinson Cancer Research Center, home to three Nobel laureates, interdisciplinary teams of world-renowned scientists seek new and innovative ways to prevent, diagnose and treat cancer, HIV/AIDS and other life-threatening diseases. Fred Hutch's pioneering work in bone marrow transplantation led to the development of immunotherapy, which harnesses the power of the immune system to treat cancer. An independent, nonprofit research institute based in Seattle, Fred Hutch houses the nation's first and largest cancer prevention research program, as well as the clinical coordinating center of the Women's Health Initiative and the international headquarters of the HIV Vaccine Trials Network.

Careers Start Here.
The Prlic lab at the Vaccine and Infectious Disease Research Division is recruiting a postdoctoral fellow to work on a project involving the study of T cell responses to infection or vaccination. The candidate must be responsible, organized, and self-motivated, and able to efficiently manage time and experiments. In addition, the candidate must be familiar with working with primary T cells as well as infectious agents and FACS analysis.

A PhD in immunology or cell biology and peer-reviewed, first author publications are required. Preference will be given to candidates with extensive experience in flow cytometry and working with microbial agents. The candidate must show initiative, the willingness to take up new skills and responsibilities, and be a team player. Must be willing to work with biohazardous/infectious agents (BSL2+) under carefully controlled conditions. Excellent attention to detail and the ability to work independently are essential to success in this position, as are good communication and organizational skills. Salary will be commensurate with (appropriate) experience.

If interested, please apply online at http://track.tmpservice.com/ApplyClick.aspx?id=2376244-3035-175

The Department of Radiation Oncology at the University of Pennsylvania, in direct collaboration with Varian, is seeking for an enthusiastic physicist to work in the implementation of proton arc therapy in Varian’s treatment planning system (TPS), ECLIPSE.

Current proton plans normally use a few fields (2-3) that fully cover the target to deliver dose conformably and uniformly. However, by doing this, the more biologically effective part of each beam (distal edge) is always located in the normal tissue distal to the target. The design of a treatment technique that deposits the enhanced biological portion of the beam within the treatment target, while maintaining dose uniformity and conformity, could potentially allow an enhancement of the therapeutic window of proton beams and a decrease of the impact by the proton range uncertainty on the treatment delivery. To test these hypotheses, a new proton arc treatment modality will be developed based on pencil beam scanning properties of Varian’s ProBeam. Current proton arc algorithms developed at the University of Pennsylvania will be used as the foundation for further algorithmic development with the intention of performing physical and biological dose optimization in proton rotational radiotherapy. This software-based feasibility study funded by Varian also aims at providing the hardware specs required to do proton arc therapy in pencil beam scanning mode. For this purpose, all algorithms will be implemented in ECLIPSE to calculate these parameters through the scripting API. In particular, the candidate will be involved with (but not only restricted to):

1. Development of new proton arc algorithms accounting for physical (dose) and biophysical (LET and RBE) objectives and constraints.
2. Measure dose distribution from ‘step-and-shoot’ arc plans to compare with calculated distributions by ECLIPSE

These measurements will involve dose and LET measurements, which will be contrasted against beam calculations performed with Eclipse API. LET measurements will be based on Silicon based 3D microdosimeters currently existing in the department.

We are searching for an experienced Clinical Affairs Scientist to work within the exciting field of oncology Companion Diagnostics (CDx). As a Clinical Affairs Scientist, your main responsibilities will be to determine clinical strategy in conjunction with team members, write clinical protocols, analyze data and write reports to support the clinical documentation of Companion Diagnostics (CDx)in the field of tissue-based Cancer Diagnostics. This position requires strong support to regulatory applications and scientific marketing activities. The top candidate will have a strong background in biostatistics and experience working in oncology drug, biomarker or in vitro diagnostic clinical development. The candidate will work directly with pharmaceutical partners,clinical and R&D scientists, Clinical Trial Managers and regulatory affairs to assure compliance with internal and external requirements.

The successful candidate will be measured on:

Your ability to contribute to the clinical strategy for CDx products.
Your professional interactions and communication skills with pharmaceutical partners and regulatory bodies, such as the FDA.
Your ability to work in a fast moving self-driven team.
Your ability to write and interpret clinical protocols, reports and provide data analysis.
Your ability to provide leadership and direction to the clinical affairs scientific staff. 

Postdoctoral Position Available

A postdoctoral position is immediately available for studies in neurophysiology focusing on the role of voltage-gated potassium channels in regulating hippocampal circuit development and function.  The candidate will be working with a team of highly interactive electrophysiologists and molecular biologists at the Eunice Kennedy Shriver National Institutes of Child Health and Human Development (NICHD), National Institues of Health (NIH). 

 Skills and Qualifications: 

• PhD and/or M.D in Neuroscience or related discipline
• Demonstrated expertise in standard and advanced neuronal electrophysiology recordings and familiarity with rodent surgical procedures
• Preferred skills, though not required, include experience in mouse models, imaging and  morphological analyses, and animal behavior experiments
• Interest in neuronal and circuit development, synaptic physiology and behavior

Successful candidates will be highly motivated, have strong work ethics and ability to work independently. Full Federal benefits including salary, leave, health and life insurance, long-term care insurance, retirement, and savings plan (401k equivalent) will be provided. Salary is commensurate with research experience and accomplishments.

Interested applicants should submit curriculum vitae, bibliography, a statement of research interests, and three letters of reference to: Dr. Dax Hoffman, Molecular Neurophysiology and Biophysics Section, NICHD, NIH , by clicking on the "APPLY" button. 

HHS, NIH, and NICHD are Equal Opportunity Employers.

Seeking a post-doctoral research associate to develop projects that examine how tissue fibroblasts amplify inflammation in autoimmune diseases.

Our focus is to use mouse disease models and human translational studies to define fibroblast populations in rheumatoid arthritis and inflammatory bowel disease. Specifically, we seek to determine how specific fibroblast populations contribute to chronic inflammation by amplifying immune responses and directly damaging tissue structure. Ongoing areas of interest include cadherin biology, growth factor receptor pathways, genetic regulation of IL-6 expression, and macrophage-fibroblast interactions.

 PRIMARY DUTIES AND RESPONSIBILITIES (Essential Functions): The primary responsibility of the post-doctoral fellow will be to conceive, design, and analyze studies pertaining to the effect of neurodegenerative disease on structural (e.g., volumetric imaging and diffusion tensor imaging [DTI]) and functional (e.g., blood oxygen level dependent [BOLD] imaging and arterial spin labeling [ASL]) brain organization. Anticipated activities entail development and implementation of new analytic strategies to facilitate understanding of disease in the human brain, integration of large multi-modal imaging datasets, and analysis of the relationship between brain imaging markers and cognition or clinical status. Strong written communication skills are required. Attention to detail, organizational capability, and the ability to handle multiple concurrent tasks are essential. The post-doctoral fellow is expected to be able to work independently as well as part of a team in a fast paced environment.

PRIMARY DUTIES AND RESPONSIBILITIES (Essential Functions):

The primary responsibility of the research assistant will be to archive/organize images (large multi-modal imaging datasets) and process/analyze multi-modal neuroimaging data. The research assistant will assist in various lab maintenance and organizational duties including tracking project progress, meet grant deadlines, and anticipate project needs.

• One of the Asia-Pacific’s leading research intensive Universities
• Strong regional and global engagement
• Cutting edge facilities and equipment

At UNSW, we pride ourselves on being a workplace where the best people come to do their best work.

The School of Psychiatry is widely reputed as the pre-eminent psychiatric research department in the country, and one of the leading university groups internationally. It is located at the UNSW teaching hospitals at various metropolitan sites in the Sydney region and in rural New South Wales.

About the role

• $69,341 - $92,453 plus 9.5% superannuation and leave loading
• Fixed Term for 12 months with a good opportunity of renewal
• Full-time (35 hours per week)

The Post-Doctoral Fellow role is responsible for the coordination and management an international study to identify the genetic determinants of small vessel disease in the brainwork. The incumbent will be responsible for the implementation and testing a computer program pipeline that will be used to analyse brain white matter lesions, white matter hyperintensities (WHMs) and lacunes. The incumbent will process structural brain MRI scans using the completed pipeline and manage the large MRI database, and be involved in other neuroimaging research and its association with genetics. This position is located in the NeuroImaging Lab (NiL) at the Centre for Healthy Brain Ageing, UNSW Randwick Campus.

Cures Start Here.
At Fred Hutchinson Cancer Research Center, home to three Nobel laureates, interdisciplinary teams of world-renowned scientists seek new and innovative ways to prevent, diagnose and treat cancer, HIV/AIDS and other life-threatening diseases. Fred Hutch's pioneering work in bone marrow transplantation led to the development of immunotherapy, which harnesses the power of the immune system to treat cancer. An independent, nonprofit research institute based in Seattle, Fred Hutch houses the nation's first and largest cancer prevention research program, as well as the clinical coordinating center of the Women's Health Initiative and the international headquarters of the HIV Vaccine Trials Network.

Careers Start Here.
The Prlic lab at the Vaccine and Infectious Disease Research Division is recruiting a postdoctoral fellow to work on a project involving the study of T cell responses to infection or vaccination. The candidate must be responsible, organized, and self-motivated, and able to efficiently manage time and experiments. In addition, the candidate must be familiar with working with primary T cells as well as infectious agents and FACS analysis.

2 PhD student positions are available starting immediately at the Department of Dermatology, University of Freiburg. The focus of the projects is delineation of disease mechanisms in wound healing disorder and subsequent therapy development. The students will be working in a dynamic lab with international collaborations. Active attendance of international research conferences is supported and expected. The positions are fully funded for three years.

STFC Rutherford Appleton Laboratory, Harwell, Oxfordshire

Salary £29,900 to £31,808 (dependent upon qualifications and experience)

18 Months Fixed Term

About Us

The Central Laser Facility (CLF) at the STFC Rutherford Appleton Laboratory near Oxford, UK, is a world-class centre for research in physical and life sciences. CLF houses some of the most intense lasers in the world as well as a suite of state of the art advanced laser systems that focus on life sciences. Scientists from the UK and overseas are using  the CLF to study and develop, for instance, pioneering anti-cancer treatments, innovative airport security systems, an understanding of climate change science  and, potentially, the clean, green energy of tomorrow. 

About The Role

Working in the Central Laser Facility we now have an exciting opportunity for an experienced materials scientist or engineer on an 18 month fixed term basis.  You will run a research and development programme in the area of Laser Peening using the new DiPOLE laser system developed and built by the CLF. There is significant opportunity to develop new processes and intellectual property whilst collaborating with academics and industrial end users.  

Specific duties include:

• Building and commissioning the new Laser Peening Laboratory within the CLF.
• Managing the research and development programme.
• Operating the Laser Peening System and planning/performing detailed experiments.
• Analysing the laser peened samples using state of the art test and measurement techniques in collaboration with UK academic experts.
• Building relationships with industry and potential end users whilst demonstrating capability.
• Managing own time responsibly to ensure adherence to task and project timelines.
• Making formal reports and occasional technical presentations regarding task or wider project outcomes.
• Compliance with STFC safety and quality management processes.

Closing date: July 01, 2016 

No tuition fees are charged regardless of your citizenship

Scholarship indication: $1000 (60000 RUB) per month
Benefits: subsidized accommodation, relocation package
Work conditions: full-time position, including ~10% teaching assistance, participation in projects and international conferences

Location: ITMO University, St. Petersburg, Russia with short-term visits to University of Amsterdam

Research topics:

• Theory of computational-based decision support
• Big data acquisition, fusion and analytics
• Methods and algorithms for complex systems simulation
• Identification, tuning and optimization of complex systems’ models
• High-performance implementations, computational and big data infrastructures
• Scientific visualization and virtual reality for computational-based decision support
• Problem-oriented software and virtual environments

Applications of complex systems simulation for decision support in:

• Biomedicine, including P4 medicine
• City science and urban sustainable development
• Social-based interdisciplinary applications
• Environmental Hazards Regulation

The PhD positions will be embedded in a number of projects related to Urban Complexity and Translational Medicine, but can also be on topics that are of general interest to TROIKA, including abovementioned research topics.

Scientific Advisors:

• Prof. Peter Sloot
• Prof. Alfons Hoekstra
• Prof. Alexander Boukhanovsky

Senior Lecturer (Maître d’enseignement et de recherche type 1) at the Institute of Higher Education and Research in Healthcare – IUFRS (full time position : 100%)

Starting date : January 1st, 2017 or to be agreed

Informations about the Institute of Higher Education and Research in Healthcare – IUFRS are available on the link www.unil.ch/sciences-infirmieres.

With its 260 institutes in nine faculties, RWTH Aachen University is one of the leading academic and research institutions in Europe. In winter semester 2015 / 2016, there were 43,721 students enrolled in 152 courses, including 7,904 international students from 125 different countries.

Focusing Expertise – Shaping the Future: The Jülich Aachen Research Alliance (JARA) is an innovative cooperation model between RWTH Aachen University and Forschungszentrum Jülich. This Alliance brings together an internationally respected university of technology and one of the leading national research centres in Europe.

In a joint procedure with RWTH Aachen University, Forschungszentrum Jülich is seeking a

 
DIRECTOR
for the Institute of Energy and Climate Research
– Modelling and simulation of materials in energy technology

In accordance with the “Jülich Model”, the successful applicant will also be appointed professor (grade W3) in the Faculty of Georesources and Materials Engineering at RWTH Aachen University.

Candidates are expected to have relevant experience in the fields of multiscale simulation of the micro­structure and also of the functional and structural properties of materials and composites for applications in energy technology. Expertise in scale-bridging methods (both development and applications) is of particular interest, especially in regards to the modelling of microstructure development during the synthe­sis, fabrication, operation and ageing of energy technology components. In addition to mechanical and corrosive stresses, catalytic and electrochemical reactions play an important part in the performance and lifetime of future energy technology.

Research activities of the successful candidate will be based at the Institute of Energy and Climate Research (IEK) of Forschungszentrum Jülich GmbH, where the successful candidate will head a newly formed institute in the area of modelling and simulation of materials in energy technology (IEK-13). Research activities will be closely coordinated with the materials science and technology research priorities at IEK. Opportunities for cooperation with the Peter Grünberg Institute (PGI) as well as the Jülich Super­computing Centre (JSC) exist. As well, cooperation and teaching in materials science and engineering at RWTH Aachen University is expected.

RWTH Aachen University and Forschungszentrum Jülich are equal opportunities emplo­yers and pursue a policy of excluding all types of discrimination. Applications from women scientists are parti­cu­larly welcome. Applications from women will be given preference in the case of equal suitability, qualifications and experience, unless special reasons concerning the person of a male candidate outweigh these considerations. Attention is drawn to Art. 8, para. 1, of the Equal Opportunities Act of the Federal State of North Rhine-Westphalia (LGG). Forschungszentrum Jülich has been certified as family friendly as part of the “audit berufundfamilie” initiative. RWTH Aachen University awards its “FAMOS für FAMILIE” prize to executive staff who have made a special contribution to family-friendly measures. Both institu­tions also offer support for dual career couples.

Applications from suitable candidates with disabilities are explicitly encouraged. This also holds for those with an equivalent degree of incapacity in the meaning of Art. 2 Code of Social Law (SGB) IX. RWTH Aachen University has been named as a “disability-friendly” employer for its commitment to training and employing disabled people.

Applications should be in English and should be sent with the usual documentation (CV, copies of certi­fi­cates, list of publications, teaching experience, brief summary of previous research activities including a list of third-party funding, research concept for the advertised position) preferably by email by 12.08.2016 to

Board of Directors of Forschungszentrum Jülich GmbH
52425 Jülich
Germany

To proceed please click on the ''APPLY'' button.

Further information can be found at
www.fz-juelich.de and www.rwth-aachen.de

The department of High Field Magnet is looking for:

Postdoc (f/m) (physics or chemistry) for scattering experiments at high magnetic fields

Reference No.: NP 2016/14

The High Field Magnet Department operates a unique and world leading facility to perform neutron scattering experiments at continuous high magnetic fields up to 26T – the highest continuous fields available for neutron scattering worldwide. The magnetic fields are produced by our hybrid magnet (HFM) permanently located at the EXtreme Environment Diffractometer (EXED), which is a multipurpose time-of-flight neutron instrument capable of neutron diffraction, small-angle-neutron-scattering (SANS) and spectroscopy.

We invite applications for a two and a half year postdoctoral position in the area of experimental condensed matter. The position is to use primarily the experimental techniques of x-ray and neutron scattering to explore the physics of correlated electron systems such as quantum and frustrated magnets, superconductors and multiferroic materials. Emphasis will be given to research in high magnetic fields. X-ray and neutron experiments will take place both in-house and at external sources, and bulk properties measurements can be performed in-house as complementary techniques. It is also expected that the candidate will have strong scientific interests and can perform his/her own research as well as develop collaborations with colleagues both inside and outside HZB.

The candidate will form part of the team operating the EXED instrument where neutron diffraction, SANS and spectroscopy can be performed up to fields of 26T and down to temperatures of 0.5 K. He or she should perform own experiments and support external users. He or she will contribute to the further development of the instrument, especially in the improvement of its performance and the implementation of new research areas.

What we offer

Fixed term contract for 30 months. The employment contract is based on contracts for the German civil service (TVöD-Bund).

We particularly welcome applications from women. Preference will be given to handicapped applicants provided equal suitability.

Contact

Prof. Bella Lake

Tel: +49 30 8062-42058

e-mail: bella.lake@helmholtz-berlin.de

Lab Head (m/f) Immune Modulation and Biotherapeutics Discovery Research-165123


Would you like to become a member of Boehringer Ingelheim’s newly formed team of highly skilled scientists to develop an innovative portfolio of first-in-class drugs for the treatment of cancer or autoimmune diseases? If so, seize the opportunity and join us as Lab Head Immune Modulation in Biberach an der Riss.

Duties & Responsibilities

• As a Lab Head within the department of Immune Modulation you will contribute to a culture of scientific excellence and state-of –the-art experimental models in immune modulation with an emphasis on autoimmune diseases and cancer immunology. 
• You will lead an in vitro lab and supervise 2-3 lab technicians.
• Leading exploratory and/or drug discovery projects is one of your main tasks. 
• You will also act as a member of scientific teams identifying, proposing and elaborating novel project opportunities.
• Furthermore you proactively foster cross-discipline and cross-site interaction to maximize scientific exchange. 
• You will continuously drive innovation by identifying internal opportunities and manage external collaborations.  
• In addition you have the opportunity to publish your results and present results within the organization as well as on conferences.

TITLE OF POST: Research Fellow - Centre for Pre-Hospital Research (CPR)
LOCATION: University of Limerick
REPORTS TO: Director, Centre for Pre-Hospital Research (CPR)
CONTRACT TYPE: Specific Purpose
SALARY SCALE: €51,716 p.a.

This post is subject to Garda Vetting/Police Clearance.

Applications are invited for the following position:

Faculty of Education & Health Sciences

Graduate Entry Medical School

Research Fellow - Centre for Pre-Hospital Research (CPR) – Specific Purpose Contract

Salary: €51,716 p.a.

OVERALL PURPOSE OF THE JOB:

To conduct primary research in pre-hospital emergency care, run courses for pre hospital research on research methodology and carry out a variety of project based work for the Pre-Hospital Emergency Care Council (PHECC).

DESCRIPTION:

The Centre for Pre-Hospital Research is based in the Graduate Entry Medical School, University of Limerick. The Centre provides research support to pre-hospital researchers nationally-including, (but not limited to) project design, ethics approval assistance, data handling, statistics, literature searching, and advice on submission for publication.

The post will entail working as part of a team but will require initiative and an ability to work in a self-directed manner on individual projects. The post will require some travel within Ireland with occasional overnight travel.

Research

• Promote research amongst pre-hospital practitioners.
• Undertake primary research in the area of pre-hospital practice.
• Carry out research reviews at the behest of the Pre-hospital Emergency Care Council.

Income Generation / Funding

• Extend the scope of funding sources/opportunities; develop ideas for generating income and promoting research area.

Research Management

• Where appropriate act as Project Leader - as such will act as a line and resource manager (e.g. of research teams).
• Organise and conduct meetings with researchers to clarify objectives, develop team work plans/timetables for research and support staff, communicate progress.
• Play a leadership role in mentoring.
• Run day long research courses for pre-hospital practitoners.
• Liaise with appropriate staff from affiliated organisations e.g. National Ambulance Service, Health Service Executive.

Write Up and Dissemination

• Write up research work for publication. 
• Contribute to the dissemination of research findings as appropriate to the discipline in high quality/impact peer reviewed publications, conference presentations, knowledge share events.

Supervision

• May act as co-supervisor or may be a member of a supervision panel. 
• Supervise the work of the research team if appropriate.

Policy & Standards

• Thorough knowledge and understanding of the policy, practices and procedures, relevant to the role, provision of advice to junior colleagues on policy and standards, which may include those of the broader University/sector/external sponsor or funder (e.g. Commercial Awareness, Research Ethics, Knowledge Transfer, Patents, Intellectual Property Rights, Health and Safety, Equal Opportunities & Diversity).
• Legal requirements regarding data protection and confidentiality data protection requirements.

We are looking for a highly energetic self motivated individual to support preclinical development of novel therapeutic compounds. Main responsibility for this position is method development and method validation, testing and routinely executing a number of in vitro and cellular biological assays.  This position is primary laboratory based and we envision that you will spend at least 70% of your time in the lab. You will manage the workload to meet aggressive timelines of a group of 2-4 junior scientists. You will take on both individual research projects as well as participate in larger research initiatives as part of matrix teams. Within these projects you will leverage your primary technical expertise in the area of preclinical in vitro/ in vivo assays. Knowledge of disease models, target pathways, current cancer and CNS therapeutics and/or prior experience in cancer/CNS biology desired.